KN, air conditioning and refrigeration systems are completely closed loop. Suggest you look into how that's done, but here's what I would suggest as a starting point:
- Keep the temporary reservoir as Danger suggests, basically set it up as mentioned before in order to bleed the system. Try to eliminate all high points in the design. If you have points in the system where air can collect and not be eliminated, ask yourself if it is ok for the air to remain there. If not, perhaps the entire assembly can be rotated so the high points become low points and all air can be flushed out by rotating in 3 dimensions. That's not very desirable for a production system obviously. You might consider having flexible lines in a few points so parts of the system can be rotated without moving other parts of the system. If so I'd recommend metal bellows hoses as opposed to plastic since plastic is very slightly permeable to air.
- To seal the system, you will need a bypass around the reservoir and back to the pump suction which is valved off when purging. It would look like this: imagine there not being a reservoir, the flow comes from the radiator which is rejecting the heat, goes through a T in the line (we'll come back to this) through a valve (valve A), another T in the line, and into the pump. The first T goes off through another valve (B) and into the reservoir. The water in the reservoir exits at the bottom, goes through another valve (C) and into the T at the pump suction. Run/cycle the system with A closed, B & C open till all air is out, then shut off the pump, close B & C, and open A. Remove the temporary reservoir by removing at the outlet of B and inlet of C (B & C are part of the cooling system). Cap or plug the lines. Another way lines are plugged is to have a copper line, crimp it closed, cut it and solder the end closed.
- Because this is a completely sealed system, you can't afford mechanical seals such as O-rings. The valve can be bellows or diaphragm sealed. Use metal bellows/diaphragms, not elastomer. The pump similarly shouldn't have external seals, use a canned pump such as the scroll pumps used in A/C systems.
- I would still be a bit concerned about thermal expansion of the water. Perhaps you'd want to test the apparatus without any feature to compensate, and if it becomes a problem, install a fully sealed accumulator such as a metal bellows sealed one.
Hope that helps.