A structure's ability to withstand vibration cycles is influenced by the amplitude and frequency of the vibrations, with the number of cycles to failure (N) following an exponential relationship with cycle amplitude. Doubling the vibration amplitude affects the cycles to failure, but the specific impact cannot be quantified without detailed material properties. The S-N curve, which plots this relationship, is material-dependent and primarily applies to high-cycle fatigue, where loading remains within the elastic regime. In contrast, low-cycle fatigue involves higher stresses and requires a different analysis based on plastic strain. Frequency does not significantly impact the S-N relationship, serving more as a factor in the strain rate sensitivity index.