[Edit, Dec 22] Science selected cosmic convergence (observation of the collision of two neutron stars) as their Breakthrough of the Year. The winner of the people's choice was gene therapy success (successful clinical trial of using gene therapy to treat childhood neuromuscular disease): http://vis.sciencemag.org/breakthrough2017/ [Edit, Dec 4] Vote for the finalists for Breakthrough of the Year: http://www.sciencemag.org/news/2017/12/finalists-are-vote-people-s-choice-breakthrough-year Science Magazine is holding its annual vote for the people's choice for Breakthrough of the Year, which will accompany their own choice. Voting is open until Dec 3. You can vote here: http://www.sciencemag.org/news/2017/11/choose-your-breakthrough-year The choices are: Fixing tiny mutations (using CRISPR to edit DNA and RNA) Human origins pushed back (discovery of a ~300,000 year old Homo sapiens skull in Morocco) A drug for many cancers (FDA approval of a new cancer immunotherapy drug) Gene therapy success (successful clinical trial to treat childhood neuromuscual disease) Biology preprints take off (increased use of prepublication servers similar to arXiv in biology) Artificial intelligence masters poker (two artificial intelligence programs were able to beat professional poker players) Oldest ice core (scientists drilled a 2.7-million-year-old ice core from Antarctica) Cosmic convergence (observation of the collision of two neutron stars) A new great ape (identification of a new species of orangutan in Sumatra) Pint-sized neutrino detector (A detector the size of a milk jug observed neutrinos) Cassini's grand finale (the Cassini spacecraft ends its 13-year mission by plunging into Saturn) Life at the atomic level (using cryo-electron microscopy to visualize the atomic structures of important biomolecules) What is your choice for the scientific breakthrough of 2017? Did the editors at Science not list your favorite scientific discovery?