To determine the resultant temperature of water mixing at different flow rates, the mass and energy balance equation is applied, specifically using enthalpy values for the respective flow rates. The equation h_3 = (m_dot1*h1 + m_dot2*h2) / (m_dot1 + m_dot2) is crucial, where m_dot represents mass flow rates and h represents enthalpy. It's important to ensure that the inlet temperatures are below the saturation temperature of water at the specified pressure to use this method accurately. If the enthalpy at the exit does not match a value in the steam table, interpolation can be used for a more precise temperature. This approach is more reliable than simply calculating a weighted average.