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How can I calculate the average gas flow on a syringe that was compressed over time, if the starting and ending pressure and volume are known?

I am guessing there must be an equation which can relate these variables. So for instance if I started at 50mL, with a pressure of 5bar and after 10 minutes the syringe was at 40mL with a pressure of 10bar, what was the average gas flow? Thanks in advance.