The integral I=\int \frac{\sqrt{\sqrt{x^4+1}-x^2}}{x^4+1}\,{\rm dx} can be simplified by substituting x^2 = \sinh t, leading to I=\int \frac{\sqrt{\coth t -1}}{\cosh t} dt. Using Mathematica may yield a complex expression involving elliptic integrals, but it has been determined that the integral can actually be expressed in terms of elementary functions. The substitution method proved effective in solving the integral. The discussion highlights the importance of strategic substitutions in integral calculus.