The volume to surface area ratio of a sphere can be calculated using the formulas for volume, V = (4/3)πr^3, and surface area, A = 4πr^2. The ratio V/A simplifies to r/3, indicating that the ratio depends on the radius of the sphere. The discussion highlights a common confusion in calculating this ratio, but the solution is straightforward once the formulas are applied. Understanding this ratio is essential for various applications in geometry and physics. The conversation emphasizes the simplicity of the calculation once the correct approach is recognized.