The Wheatstone bridge achieves maximum sensitivity when all four resistances (A, B, C, and D) are equal due to the balance condition A/B = C/D, which minimizes the current through the galvanometer. This balance leads to a situation where small changes in resistance produce the largest changes in current, enhancing sensitivity. The sensitivity can be mathematically defined as the derivative of current with respect to any resistance, indicating that equal resistances yield optimal sensitivity. By analyzing the system of equations derived from the sensitivity definition, it becomes clear that equal values provide the best performance. Thus, maintaining equal resistances is crucial for achieving high sensitivity in Wheatstone bridge applications.