Why Are Some mRNA Transcripts Bigger Than Others?

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Variations in the size of mRNA transcripts from the same gene can be attributed to differences in poly(A) tail length and alternative splicing events. Poly(A) tails may vary due to differing degrees of degradation, impacting transcript size. Additionally, alternative splicing allows for the production of multiple mRNA isoforms, leading to transcripts of different lengths. These mechanisms contribute to the diversity of mRNA transcripts in gene expression. Understanding these processes is crucial for comprehending gene regulation and expression dynamics.
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Homework Statement


After isolating the same mRNA transcripts of the same gene, why are some transcripts bigger than others?

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The Attempt at a Solution

 
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Consider what happens to mRNAs after they are initially synthesized.
 
polyA tail?
 
Yes, the poly(A) tails can be of differing length (e.g. some poly(A) tails may have undergone more degradation than others). The mRNAs can also be alternatively spliced resulting in differently sized transcripts.
 
Thread 'Confusion regarding a chemical kinetics problem'

Thread 'Confusion regarding a chemical kinetics problem'

TL;DR Summary: cannot find out error in solution proposed. [![question with rate laws][1]][1] Now the rate law for the reaction (i.e reaction rate) can be written as: $$ R= k[N_2O_5] $$ my main question is, WHAT is this reaction equal to? what I mean here is, whether $$k[N_2O_5]= -d[N_2O_5]/dt$$ or is it $$k[N_2O_5]= -1/2 \frac{d}{dt} [N_2O_5] $$ ? The latter seems to be more apt, as the reaction rate must be -1/2 (disappearance rate of N2O5), which adheres to the stoichiometry of the...
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