Why does venous block cause infarction?

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Blocked veins can lead to tissue necrosis due to congestion and increased back pressure, which hampers arterial blood flow and oxygen delivery, despite arteries still being able to supply oxygen. This situation creates a scenario where oxygen levels in the stagnant blood decrease, contributing to tissue damage. The pathogenesis of cerebral venous infarction differs from that of cerebral arterial ischemic infarction, primarily due to the mechanisms of blood flow and pressure. Hemorrhagic infarcts in cerebral venous infarction occur because stagnant blood can lead to increased pressure and rupture of vessels. Understanding these dynamics is crucial for grasping the complexities of vascular health.
sameeralord
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Hi guys,

I know this is a simple question. But when an artery is blocked it is easier to understand because, less oxygen goes to tissue so, necrosis of tissue. But when a vein is blocked, only the draining is affected, the arteries are still able to supply oxygen, but why does necrosis still occur. I'm assuming it is because when a vein is blocked, it leads to congestion, increased back pressure, which makes it difficult for arterial blood to come and perfuse tissue. Just asked to clarify (I know this is probably a pretty obvious stupid question, but I like to get it clarified). Thanks :smile:

While we are at it, if you know something about this, please tell me

Does the pathogenesis of cerebral venous infarction differ considerably from the pathogenesis of cerebral arterial ischemic infarction. Why does a haemorrhagic infarct occur in cerbral venous infarction.
 
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You can simply see this as "what flows in must flow out", because if that is not the case some volume of blood will stay in the same area for a prolonged time and the transfer of oxygen to the tissue from this volume of blood will go down as their oxygen levels get closer together.
 
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