The electric field inside a cyclotron is negligible because the particles are surrounded by two conducting plates at the same potential, resulting in no net electric field in that region. Acceleration occurs in the gap between the Dees, where an alternating RF electric field exists, allowing particles to gain energy as they cross the gap at the right timing. The magnetic field keeps the particles in circular motion, ensuring they do not collide with the plates if the electric field inside the Dees is zero. The cancellation of electric fields occurs due to the geometry of the Dees and their potential difference, which creates a field only in the acceleration gap. Understanding these dynamics is crucial for the effective operation of RF particle accelerators.