Why is there a link between sleep and the immune system?

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Lack of sleep significantly weakens the immune system, despite the body's ability to rest without sleeping. The connection between sleep and immune function is crucial, as sleep deprivation can lead to a decline in immune response. Research indicates that sleep plays a vital role in the regulation of immune processes, affecting the production and activity of immune cells. While the immune system operates independently of mood, sleep deprivation can disrupt its efficiency. For further reading, a relevant study can be found at the provided link, which highlights the impact of sleep on immune health.
star apple
When you don't sleep.. your immune system gets weak.. but even if you stay still or rest without sleeping.. your body should theoretically be in a restful state.. so the immune system being products of cells, Brownian motion and thermodynamics, etc. should not be related to sleep..

Yet it is.. why? What is the connection of sleep to the immune system?
 
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You need to provide a reference regarding the idea that lack of sleep weakens the immune system.
Sure, lack of sleep can cause mood disorders in humans, but then the immune system works by itself regardless of it's owners mood.
 

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