Why optically active molecules rotate light?

AI Thread Summary
Optically active molecules, such as R-alanine, can rotate polarized light due to their chiral nature, which means they cannot be superimposed on their mirror images. The direction of light rotation is dependent on the spatial arrangement of the molecule's functional groups, such as the COOH group in R-alanine. When considering a helical structure, like helicenes, the orientation of the helix affects how it interacts with light. A 180-degree rotation of a helix alters its orientation but does not change its intrinsic chiral properties. This highlights the complexity and significance of molecular structure in optical activity.
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Say, we have a solution of pure form of R-alanine. Say, the molecule has it's COOH group directed along positive y-axis and rotates the z-polarized light clockwise - the question is why the same molecule with it's COOH group in negative y direction won't do the opposite.
 
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Consider a simpler example, a helix. How does a helix look like when you rotate it by 180 deg?
An example of a chiral molecule with a helical structure are the helicenes:
http://en.wikipedia.org/wiki/Helicene
 
Fascinating :). Thank you for the reply, DrDu.
 
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