Would you tell me what it is (cd4+ T-cell populations)?

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CD4+ T-cell populations are a type of T-cell characterized by the expression of the CD4 receptor on their surface. This receptor interacts with MHC class II (MHCII) molecules, which present extracellular peptides. The T-cell receptor (TCR) on CD4+ T-cells recognizes these peptides, enabling the cell to receive signals that stimulate its activation. In contrast, CD8+ T-cells recognize MHC class I (MHCI) molecules, which present intracellular peptides, such as those from viral infections. Immature thymocytes express both CD4 and CD8, but upon maturation and exiting the thymus, they differentiate into either CD4+ or CD8+ T-cells.
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Would you tell me what it is (cd4+ T-cell populations)?
 
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It is a population of T-cell that express CD4 receptor on its surface.
 
The CD4 molecule recognizes MHCII, which is a molecule that presents peptides from outside of the cell. The T-cell receptor (TCR) recognizes the peptide presented by the MHCII. Together the CD4 and the TCR are able to relay a signal into the cell and stimulate the T-cell.

There are also cells that are CD8+, which means that they recognize MHCI. MHCI presents peptides from inside the cell, for instance when a cell is infected with a virus or by a bacterial lysteria infection.

Immature thymocytes are CD4+ and CD8+, when they leave the thymus they are either CD4+ or CD8+.
 

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