Metathesis: The Dance of Carbon Atoms - 2005 Nobel Prize in Chemistry

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The 2005 Nobel Prize in Chemistry was awarded jointly to Yves Chauvin, Robert H. Grubbs, and Richard R. Schrock for their significant contributions to the development of the metathesis method in organic synthesis. This innovative technique has transformed organic chemistry, enabling the efficient production of a wide range of new molecules, including pharmaceuticals. Metathesis involves breaking and forming double bonds between carbon atoms, allowing for the rearrangement of atom groups with the help of catalysts. This process has opened up vast possibilities for synthetic chemistry, emphasizing creativity in molecule design. The discussion also highlights the personal qualities of Grubbs, noting his approachable nature and commitment to mentoring students, reflecting a blend of professional achievement and humility.
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http://nobelprize.org/chemistry/laureates/2005/index.html

The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry for 2005 jointly to

Yves Chauvin
Institut Français du Pétrole, Rueil-Malmaison, France,

Robert H. Grubbs
California Institute of Technology (Caltech), Pasadena, CA, USA and

Richard R. Schrock
Massachusetts Institute of Technology (MIT), Cambridge, MA, USA

"for the development of the metathesis method in organic synthesis".

Metathesis – a change-your-partners dance

This year's Nobel Prize Laureates in chemistry have made metathesis into one of organic chemistry's most important reactions. Fantastic opportunities have been created for producing many new molecules - pharmaceuticals, for example. Imagination will soon be the only limit to what molecules can be built!

Organic substances contain the element carbon. Carbon atoms can form long chains and rings, bind other elements such as hydrogen and oxygen, form double bonds, etc. All life on Earth is based on these carbon compounds, but they can also be produced artificially through organic synthesis.

The word metathesis means 'change-places'. In metathesis reactions, double bonds are broken and made between carbon atoms in ways that cause atom groups to change places. This happens with the assistance of special catalyst molecules. Metathesis can be compared to a dance in which the couples change partners.

See - http://en.wikipedia.org/wiki/Olefin_metathesis
 
Chemistry news on Phys.org
I received an email from CalTech about this earlier today. It's pretty interesting.
 
YEAH! Way to go France!
 
I once had lunch with Bob Grubbs.

He's a pretty cool guy.
 
I agree. Grubbs is a heck of a nice guy and really un-pretentious about his work. I saw him at lunch yesterday and he was sitting at a table with three or four grad students from his lab. I thought that was really cool; here this guy just won the biggest award there is for chemistry and he chooses to just be a regular guy. Good for him.
 
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