The discussion explores the nature of reference frames in defining distances, questioning whether distances can exist independently of a coordinate system. It suggests that while a single absolute frame may theoretically exist, practical measurements of distance can occur without it, relying instead on relative distances between particles. The conversation also delves into the relationship between space and time, emphasizing their interdependence as described by relativity, and how higher dimensions can unify physical laws. Additionally, it touches on the dimensionality of worldlines and the implications of compactified dimensions in theories like Kaluza-Klein. The overall theme centers on the complexities of measuring distances and the foundational principles of spacetime in physics.