Hormones can indeed be modified through the regulation of feedback loops, where one hormone influences the secretion of another, ultimately affecting the original hormone's levels. The discussion centers on the possibility of decreasing somatotropin (STH) in rabbits to study the resulting health effects, including potential sicknesses or cures. The individual seeks guidance on how to effectively decrease STH for their project, indicating a need for more specific methodologies or approaches to achieve this hormonal modification.