Do Any Bacteria or Archaea Use Metabolic Pathways Other Than Glycolysis?

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Discussion Overview

The discussion revolves around the metabolic pathways utilized by bacteria and archaea, specifically focusing on whether any organisms exist that do not employ glycolysis or its variants. Participants express interest in the evolutionary implications of these pathways, including the possibility of convergent evolution among different metabolic strategies.

Discussion Character

  • Exploratory
  • Debate/contested
  • Conceptual clarification

Main Points Raised

  • One participant inquires about the existence of bacteria or archaea that utilize metabolic pathways other than glycolysis, seeking details on any such organisms and their evolutionary background.
  • Another participant mentions hydrotropic methanogens, which use carbon dioxide and hydrogen for energy and do not appear to employ glycolysis in their metabolic processes.
  • Questions are raised regarding other metabolic processes such as photosynthesis, chemosynthesis, and the pentose phosphate pathway, suggesting these may also be relevant to the discussion.
  • There is a repeated inquiry into the evidence for convergent evolution in non-glycolysis pathways, with one participant noting that this topic is still under exploration in molecular biology.
  • Some participants express uncertainty about the current understanding of the evolution of various metabolic pathways, indicating that definitive answers may be elusive.

Areas of Agreement / Disagreement

Participants generally agree that the exploration of non-glycolysis pathways and their evolutionary implications is ongoing, and there is no consensus on the existence of convergent evolution in this context. Multiple viewpoints and uncertainties remain present in the discussion.

Contextual Notes

The discussion highlights limitations in the current understanding of metabolic pathways and their evolutionary histories, with participants acknowledging the complexity and potential for ongoing research in this area.

Nereid
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One more question about the evolution of life, but perhaps not in the Archaen or Proterozoic.

Are there any bacteria or archaea known to use metabolic pathways other than (one or more variants of) glycolysis? Which do not use any form of glycolysis? If so, details please!

I'm particularly interested in whether these cases, if there are any, evolved from a common ancestor, or whether they are examples of convergent evolution.
 
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methanogens

This was thought to be correct when I researched the topic several years ago --

Hydrotropic methanogens use carbon dioxide as a source of carbon; hydrogen as a source of energy. Carbon dioxide is reduced by hydrogen to produce methane. The methane is turn gives rise to a proton motive force across a membrane, which is used to generate ATP – a key source of cellular energy.

No mention of glycolysis.

You can start here:

http://jfa.bio.qmul.ac.uk/lectures/cell_biology_and_developmental_genetics/Hydrogen_hyp.pdf
 
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What about photosynthesis?
Or chemosythesis?
Or pentose phosphate?
 
Thanks jim macnamara and zomgwtf.

Is there any evidence of convergent evolution, of non-glycolysis pathways?
 
Nereid said:
Thanks jim macnamara and zomgwtf.

Is there any evidence of convergent evolution, of non-glycolysis pathways?

I think that is an issue that is still being explored by the molecular biology crowd. Given how often the assumption that convergent evolution must not happen is turned on its head by that field, I wouldn't be shocked if it turned out that there is such convergence. I can't find, nor have I heard of anything definitive in the field, yet, which supports or refutes the notion.
 
nismaratwork said:
I think that is an issue that is still being explored by the molecular biology crowd. Given how often the assumption that convergent evolution must not happen is turned on its head by that field, I wouldn't be shocked if it turned out that there is such convergence. I can't find, nor have I heard of anything definitive in the field, yet, which supports or refutes the notion.

I agree. I haven't gone into that much depth in gylcolosis but I'm pretty sure our understanding of the evolution of various pathways is pretty limited.

I'm not even sure this will ever be definitively answered although it's agood question.
 

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