Einstein's mass-energy relation, expressed as E = mc^2, indicates that mass is a form of energy, with E representing energy, m representing mass, and c denoting the speed of light (approximately 3.0 x 10^8 m/s). The equation quantifies the amount of mass-energy stored in an object, which can be transformed into kinetic energy when the object is in motion. This relation holds true primarily for objects at rest or moving at low speeds relative to light. For objects in motion, the kinetic energy is described by a more complex equation, E = mc^2(1/(1-v^2/c^2)-1), which simplifies to E = mc^2 when velocity (v) is zero. Understanding this relationship is crucial for grasping the principles of physics related to energy and motion.