A high energy free electron can indeed collide with a low energy photon, resulting in Compton scattering, where the photon gains energy and the electron recoils. This process can be replicated in a laboratory setting, particularly when a high energy electron beam interacts with a laser beam. The energy gain for the photon is approximately 4γ², depending on the reference frame used. The discussion highlights the importance of understanding the Lorentz frame changes in these collisions, as they affect the energy dynamics of the photon. Overall, the interaction is consistent with established principles of quantum mechanics and relativistic physics.