How do ointments work when we have burns on the skin

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Ointments for treating skin burns offer several advantages, including the delivery of antibiotics, limited barrier protection against pathogens, and physical relief through numbing agents or lubrication of scabs. However, there are notable drawbacks. Ointments can restrict oxygen access, potentially promoting harmful bacteria in severe burns. The natural scaling of the skin often serves as a better barrier against pathogens. Additionally, improper application, such as using ointments without washing hands, can introduce bacteria into the wound, particularly with products like aloe vera that lack broad germicidal properties. Maintaining sterility during application is crucial to prevent cross-contamination. There is also a suggestion that ointments could be developed to enhance p53 upregulation for better healing outcomes.
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how do ointments work when we have burns on the skin
 
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pros:

1. they can be vectors for antibiotic delivery
2. they can provide limited barrier protection against pathogens entering into the wound
3. they can provide relief physically by delivering numbing agents such as any ingredient with the suffix 'caine or by lubricating the otherwise scaly grindage associated with scabs.

cons:
1.they can limit oxygen access which can foster bacteria that are unhelpful or dangerous if a burn is really bad.
2. the natural scaling is a better barrier to pathogens
3. people tend to put them on without washing hands first, in this case the gel medium may hold bacteria against the wound, especially in the case of aloe vera which is not broadly germicidal. even if you did wash your hands, 99% of the time you rub the tip of the applicator which is just holdover bacteria from previous wounds...then they get cross contaminated into the new one so sterility is needed when using them and handling the containers.
 
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Cant they also help upregulate p53? if not, they should make some that can =)

p.s. the medical term for burns is "ouchy"
 
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Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom

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