The string in a friction experiment must be parallel to the horizontal plane to ensure accurate measurement of the frictional force related to the normal force. If the string is angled upwards, it reduces the normal force by partially supporting the weights, leading to an underestimation of friction. Conversely, if the string angles downwards, it increases the normal force, resulting in an overestimation of friction. Maintaining a parallel orientation allows for consistent and reliable readings on the scale, directly reflecting the actual force required to overcome friction. Accurate string placement is crucial for valid experimental results.