Organic Chemistry: Formamide + Formic Acid

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SUMMARY

The discussion centers on the interaction between aldehydes, ketones, formamide (HCONH2), and formic acid (HCOOH). It concludes that the amide is unlikely to facilitate aldol condensations due to its insufficient reactivity. Instead, small-scale acid-base reactions and the formation of solid adducts are anticipated. Additionally, considerations regarding the boiling points and melting points of the substances involved are crucial for effective mixing and analysis.

PREREQUISITES
  • Understanding of organic compounds, specifically aldehydes and ketones
  • Knowledge of amide reactivity in organic chemistry
  • Familiarity with acid-base reactions
  • Basic principles of boiling and melting point analysis
NEXT STEPS
  • Research the reactivity of amides in organic reactions
  • Study the mechanisms of acid-base reactions involving formic acid
  • Explore the physical properties of aldehydes and ketones
  • Investigate the formation and properties of solid adducts in organic chemistry
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Chemistry students, organic chemists, and researchers interested in reaction mechanisms involving aldehydes, ketones, and amides.

maverick280857
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Hi,

I want to know what happens when a mixture containing aldehyde(s) and ketone(s) is introduced to a mixture of formamide HCONH_2 and formic acid HCOOH.

Do both aldehyde and ketone react? Or does only one react?

Eagerly awaiting a response...

Thanks and Cheers
Vivek
 
Last edited:
Chemistry news on Phys.org
nothing that I can think of, the amide won't be strong enough for aldol condensations...probably small scale acid base reactions at the most and formation of solid adducts. You would also have to analyze the boiling point/mp of these substances and consider how you would actually mix all of them together in the first place...Interesting physical and chemical dynamics may occur
 

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