I'm assuming your R is the group of reals under addition and R* is the group of nonzero reals under multiplication.
So, to your question. All you've shown is that the particular function f:R->R* defined by f(x)=e^x isn't an isomorphism. However, this does not imply that R isn't isomorphic to R^*. For example, consider the groups G=\{e,a^2,a^3,\ldots\} and (\mathbb{Z},+). The bijection g:G->Z defined by
f(a^n)=<br />
\begin{cases}<br />
2&\text{if } n=1\\<br />
1&\text{if } n=2\\<br />
n&\text{else}<br />
\end{cases}<br />
is clearly not an isomorphism, yet \mathbb{Z}\cong G.
The usual process to determine that two groups are not isomorphic is to find some algebraic property (i.e. one that would be conserved under isomorphism) that is not common to each group. For R and R*, try examining the properties of the element -1\in \mathbb{R}^*. Is there an element in R with the same properties (under addition)?