Vanadium 50 said:
First, the Misra and Sudarshan effect is negligibly small. I don't believe it has even been observed in nuclear transitions (although it has in atomic transitions).
Google search for the exact phrase "Misra and Sudarshan effect" or "Misra-Sudarshan effect" gave nothing but your post. If, however, you mean "Quantum Zeno effect", this is not exactly what I had in mind. Khalfin's results on decay nonexponentiality (which precede Misra-Sudarshan work by 10-20 years) are applicable both to very short times, which may be relevant to the Quantum Zeno effect, and to very long times, which does not seem relevant to QZE. Furthermore, I said myself that "It is very difficult to observe the deviations from the exponential law though", so what's your point?
Vanadium 50 said:
Second, no matter how you define a lifetime in the case of the practically-but-not-theoretically exponential decay, the answer to the OP's question is clearly "yes".
If you mean that for a "practically exponential decay" half-life "practically" does not change with time, this sounds pretty much like a tautology. My point, however, was that theoretically there is no such thing as precisely exponential decay.
Vanadium 50 said:
Splitting hairs like this doesn't make the answer to the OP's any clearer.
It makes the answer more precise though. The OP's question was "Shouldn't the half life itself change over time ?", and the correct answer is "Yes, it should." Furthermore, OP used the following interesting argument: "since the normal pdf is the one with the most entropy of information and radioactive decay increases the entropy of the material, I'm concluding the pdf itself should bias after a while." This is a purely theoretical argument, so if you answer "No, half life should not change over time" based on practical considerations, such an answer may be not just imprecise, but also confusing and misleading.
Anyway, you could accuse me of hair-splitting (although I said myself that decay nonexponentiality is very difficult to observe), but not of irrelevancy.