RNA Interference & SIR2 & SCH9 Genes

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RNA interference (RNAi) is being considered as a method to inhibit the expression of the SIR2 and SCH9 genes. The discussion highlights the uncertainty surrounding the effectiveness of RNAi for this purpose. Additionally, there is a suggestion that providing more background information and relevant resources could enhance the quality of responses to specific inquiries. The conversation also raises the question of why RNA interference might be preferred over gene deletion, hinting at potential advantages such as targeted regulation without permanent genetic alterations.
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Can RNA interference be used to stop the expression of SIR2 and SCH9 genes? Is it unknown whether or not it can?

never mind about the 3rd question found out the only difference was whether or not the change is inherited
 
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Hi Bioquest. I've noticed you've been making a lot of posts with very specific, fairly obscure questions. Perhaps you'd get a better response if you gave people more back ground information. A link to a website containing pertinent information would be especially helpful.
 
Why use RNA interference instead of deleting a gene? What could/would make that more beneficial?
 
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https://www.discovermagazine.com/the-deadliest-spider-in-the-world-ends-lives-in-hours-but-its-venom-may-inspire-medical-miracles-48107 https://en.wikipedia.org/wiki/Versutoxin#Mechanism_behind_Neurotoxic_Properties https://www.sciencedirect.com/science/article/abs/pii/S0028390817301557 (subscription or purchase requred) he structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel...
Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom

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