By STEM I mean science, technology, engineering and math. By a bible, I mean a book which is comprehensive, big and heavy (both physically and intellectually), authoritative, and generally highly respected in the community as the standard book that contains more-or-less everything one needs to know about the subject. The examples in physics are: - general physics: The Feynman Lectures on Physics (3 volumes) - classical mechanics: H. Goldstein et al, Classical Mechanics - classical electromagnetism: J.D. Jackson, Classical Electrodynamics - general relativity: C.W Misner, K.S. Thorne and J.A. Wheeler, Gravitation - quantum mechanics: Surprisingly, I don't know which of the standard QM textbooks would deserve this title. - quantum information and computation: M.A. Nielsen and I.L. Chuang, Quantum Computation and Quantum Information - quantum field theory: the old testament: S. Weinberg, The Quantum Theory of Fields Volume I the new testament: S. Weinberg, The Quantum Theory of Fields Volume II (There is also the Volume III on supersymmetry, but it does not have such a high reputation.) What are your examples?