Unraveling the Mystery of DNA's Self-Replication

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The discussion centers on the unique self-replicating properties of DNA and RNA compared to other macromolecules like proteins and simpler molecules such as benzene. It is noted that DNA does not replicate on its own; it requires proteins (enzymes) and RNA for the process. While proteins serve as effective catalysts, they lack the complexity needed for self-replication. RNA, on the other hand, possesses the ability to catalyze reactions and replicate itself. The conversation highlights DNA's structural properties, likening it to a zipper that allows for precise electrostatic interactions between molecules, facilitating replication through a templated process. This specificity in molecular interaction is what sets DNA and RNA apart from other molecules.
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Hi All

Why DNA molecules alone replicates itself were does self property of ( memory ) to replicate comes from ? why not other macro moloecules like proteins ( expect pirons :biggrin: ) don't replicate like DNA :confused:
 
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DNA does not replicate itself, it needs proteins (enzyme) and RNA. Proteins are excellent catalysts, but fail to catalyze processes complex enough to recreate themselves, individually. RNA is capable of both catalysis and self-replication.
 
why not applicable to simple micro molecules

:bugeye:

why not a simple benzene molecule can be catalysed and replicated why DNA /RNA alone have such property
 
Because DNA is like a zipper, two molecules through electrostatic interaction are able to fit perfectly into each other.. this property is used for the replication, you're building a new molecule from a template like lego.
 
Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom
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