Evo wrote:
Please read our guidelines on overly speculative posts, especially when you have provided no recognized scientific research.
My apologies for not following protocal. Firstly, I don't believe that my original post was overly speculative. Below are the titles and links to numerous articles, studies, and research (along with brief snippets) on the subject of my original query, "Do vaccines and pharmaceuticals block/impede neurotransmitters?"
From my own research (done in a few hours) it appears that yes, vaccines do affect and potentially inhibit neurotransmitters.
CHroot wrote:
Vaccines are composed of viral particles (usually broken apart or otherwise killed) in a suspension with some preservatives. The viral particles themselves will not penetrate the blood-brain barrier, and thus cannot affect synapses or neural function directly. There was some fear that mercury-based preservatives could cause developmental problems, so those preservatives are no longer used. No current vaccines use mercury-containing preservatives.
There is no credible link between autism and vaccination.
You are incorrect on a couple of issues. There are vaccines (annual flu vaccine) that contain mercury. Most other vaccines no longer use mercury, however, they have replaced it the aluminum and aluminum can penetrate the BBB as it is recongized as iron. And, though aluminum has been considered safe, a number of the studies below reflect otherwise.
Please correct the plausibility of my argument, but, from what I gather, mercury, aluminum and other heavy metals used as adjuvants in vaccines enter neurons and glial cells (astrocytes and microglia). These toxic metals can inhibit astrocyte function in the brain. They also activate microglia cells in the brain, which control brain inflammation and immunity. Once activated, the microglia secrete large amounts of neurotoxic substances such as glutamate, an excitotoxin, which adds to inflammation. The inflammation disrupts brain neurotransmitters resulting in reduced levels of serotonin, dopamine, and norepinephrine. The toxic metals can inhibit production of neurotransmitters by inhibiting: calcium-dependent neurotransmitter release, dihydroteridine reductase, nitric oxide synthase, blocking neurotransmitter amino acids, and effecting phenylalanine, tyrosine and tryptophan transport to neurons. And, recent studies show that astrocyte apoptosis may contribute to pathogenesis of many acute and chronic neurodegenerative disorders, such as cerebral ischemia, Alzheimer's disease and Parkinson's disease.
So, according to the research provided below, vaccines containing toxic metals (including aluminum) can inhibit neurotransmitters and potentially cause neurological disorders. These disorders include Autism, Alzheimers, Parkinson's, ADHD, etc... from a purely logically standpoint, injecting toxic metals into our brains can provide a harmful consequence.
The speculation is based on the potential fact that toxic metals inhibit neurotransmitters. So, every individual receiving a vaccine containing toxic metals has had their brains affected by them to a certain degree. As a result some will suffer with ADD/ADHD, while others will suffer with Parkinsons, Alzheimers, Dementia, etc..., while others deal with Restless leg syndrome, Sleep apnea, or one of the hundreds of neurological disorders, and sadly others have literally seen the lights within their children's eyes go dim as a result of Autism.
To suggest that there are no serious neurological risks associated with vaccines is simply illogical. To suggest that there are no consequences to injecting toxic metals into our bodies is also illogical. What our culture has potentially done is trade Mumps, Measles, and Rubella for Autism, Alzheimers and ADHD. Now, that's a bold speculation.
Vaccine critics & studies on vaccine autism link
http://whale.to/vaccine/mmr58.html
One in every 166 children has autism today
compared to one in every 2,500 in 1991.
Chemist says mercury linked to autism spike
http://www.whale.to/vaccine/chem.html
From the article:
He figured out that the amount of mercury in flu shots - 50,000 micrograms per
liter in the multi-dose vials - is 250 times the amount that's considered
safe for liquid hazardous waste.
Study shows a direct link between standard childhood vaccination series and autism-like symptoms in primates.
http://www.naturalnews.com/026827_autism_vaccination_vaccines.html
From the article:
While the Food and Drug Administration considers vaccines safe and lists them as such, they have done no studies into the effects of multiple vaccinations as given in the common childhood series which started in the 1990s.
Mercury In Vaccines Was Replaced With Something Even MORE Toxic http://www.americanchronicle.com/articles/view/89667
From the article:
Vaccines containing high concentrations of neurotoxic aluminum were added to the child immunization schedule when several vaccines containing mercury were removed. Two-month old babies now receive 1,225 mcg of aluminum from their vaccines -- 50 times higher than safety levels!
Every vaccine has two components, the agent that you´re seeking to elicit an immune response to, such as a measles virus, and an immune adjuvant, which enhances the immune response and is typically made from a variety of highly toxic compounds including aluminum compounds, MSG, and mercury. The purpose of immune adjuvants is to boost your immune system, or to make it react as intensely as possible for as long as possible.
How Aluminum Can Harm Your Brain?
When you or your child is injected with a vaccine, the aluminum compounds it contains accumulate not only at the site of injection but travel to your brain and accumulate there. In your brain, aluminum enters neurons and glial cells (astrocytes and microglia).
The aluminum hydroxide used in many vaccines, including hepatitis A and B, and the Pentacel cocktail for diphtheria, pertussis, tetanus, polio, and meningitis, has been clearly linked to symptoms associated with Parkinson's, ALS (Lou Gehrig's disease), and Alzheimer's.
Even a study in Pediatrics, the official journal of the American Academy of Pediatrics, admitted that: "Aluminum is now being implicated as interfering with a variety of cellular and metabolic processes in the nervous system and in other tissues." This has led some experts to suggest that aluminum in vaccines may be linked to autism.
Aluminum in Vaccines: The Neurological gamble
http://www.thinktwice.com/aluminum.pdf
From article:
Babies who follow the CDC immunization schedule are injected with nearly 5000mcg (5mg!) of aluminum by 18 months of age.
Depression and other Neurotransmitter Related Conditions- the mercury connection
http://www.flcv.com/depress.html
From article:
The levels of brain neurotransmitters such as dopamine, norepinephrine, and serotonin, appear to be major factors in controlling moods, and appear to be affected by lifestyle, diet, philosophy, and environmental factors. Some are more susceptible to depression than others, and thus more affected by diet and environmental factors.
Chronic or acute brain inflammation appears to be a primary factor in depression. The brain is very sensitive to inflammation. Disturbances in metabolic networks: e.g., immuno-inflammatory processes, insulin-glucose homeostasis, adipokine synthesis and secretion, intra-cellular signaling cascades, and
mitochondrial respiration have been shown to be major factors in depressive disorders and other chronic neurological conditions.
Inflammatory chemicals such as mercury, aluminum, and other toxic metals as well as other excitotoxins including MSG and aspartame cause high levels of free radicals, lipid peroxidation, inflammatory cytokines, and oxidative stress in the brain and cardiovascular systems. Overexposure to heavy metals like lead and mercury have been shown to induce anxiety or depression.
Mercury and other toxic metals inhibit astrocyte function in the brain and CNS, causing increased glutamate and calcium related neurotoxicity. Mercury and increased glutamate activate free radical forming processes like xanthine oxidase which produce oxygen radicals and oxidative neurological damage. Nitric oxide related toxicty caused by peroxynitrite formed by the reaction of NO with superoxide anions, which results in nitration of tyrosine residues in neurofilaments and manganese Superoxide Dimustase(SOD) has been found to cause inhibition of the
mitochondrial respiratory chain, inhibition of the glutamate transporter, and glutamate-induced neurotoxicity involved in ALS.
These inflammatory processes damage cell structures including DNA,
mitochondria, and cell membranes. They also activate microglia cells in the brain, which control brain inflammation and immunity. Once activated, the microglia secrete large amounts of neurotoxic substances such as glutamate, an excitotoxin, which adds to inflammation and stimulates the area of the brain associated with anxiety. Inflammation also disrupts brain neurotransmitters resulting in reduced levels of serotonin, dopamine, and norepinephrine. Some of the main causes of such disturbances that have been documented include vaccines, mercury, aluminum, other toxic metals, MSG, aspartame, etc.
Mercury is neurotoxic (kills or damages brain and nerve cells), generates high levels of reactive oxygen species (ROS) and oxidative stress, depletes gluatathione and thiols causing increased neurotoxicity from interactions of ROS, glutamate, and dopamine, kills or inhibits production of brain tubulin cells, inhibits production of neurotransmitters by inhibiting: calcium-dependent neurotransmitter release, dihydroteridine reductase,nitric oxide synthase, blocking neurotransmitter amino acids, and effecting phenylalanine, tyrosine and tryptophan transport to neurons. Toxic metals as well as genetic factors commonly cause systemic methylation deficiencies, which are documented to commonly be a factor in chronic conditions such as depression, autism, etc.
Numerous studies have found long-term chronic low doses of mercury cause neurological, memory, behaviour, sleep, and mood problems. Neurological problems are among the most common and serious effects of mercury, and include memory loss, moodiness, depression, anger and sudden bursts of anger/rage, self-effacement, suicidal thoughts, lack of strength/force to resolve doubts or resist obsessions or compulsions, etc. Many studies of patients with major neurological diseases have found evidence amalgam fillings may play a major role in development of conditions such as depression, schizophrenia , memory problems, and other more serious neurological diseases such as MS, ALS, Parkinson’s, and Alzheimer’s.
The Neurotoxic Effects of Aluminum
http://student.biology.arizona.edu/ad/neurotoxic.html
Evaluation of Neurotoxicity of Mercury Compounds and Aluminum in Cell Cultures
http://acta.uta.fi/english/teos.php?id=10127
From abstract:
Mercury and aluminum are neurotoxic metals with diverse effects on cellular functions in the brain. Ultimately exposure to them can lead to neural destruction and degenerative diseases.
Aluminum and Aluminum Toxicity
http://www.hbci.com/~wenonah/hydro/al.htm
From research:
Aluminum has been exempted from tesitng for safety by the FDA under a convoluted logic wherein it is classified as GRAS. (Generally Regarded As Safe.) It has never been tested by the FDA on its safety and there are NO restrictions whatever on the amount or use of aluminum.
Aluminum neurotoxicity in preterm infants receiving intravenous-feeding solutions. In preterm infants, prolonged intravenous feeding with solutions containing aluminum is associated with impaired neurologic development.
Aluminum-induced apoptosis in cultured astrocytes and its effect on calcium homeostasis
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6SYR-424T6M2-4&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1102745418&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=3517b96b88f822e0a1316ce978aa87aa
From Abstract:
Aluminum exposure and apoptotic cell death has been implicated in several neurodegenerative conditions including Alzheimer’s disease. In this study, we use cultured astrocytes to investigate the ability of aluminum to induce the apoptosis of astrocytes.
The study's findings suggest that aluminum induce and block selectively the apoptosis of astrocytes, which depend upon the concentrations of aluminum.
Astrocyte apoptosis: implications for neuroprotection.
http://www.ncbi.nlm.nih.gov/pubmed/15063528
Astrocytes, the most abundant glial cell types in the brain, provide metabolic and trophic support to neurons and modulate synaptic activity. Accordingly, impairment in these astrocyte functions can critically influence neuronal survival. Recent studies show that astrocyte apoptosis may contribute to pathogenesis of many acute and chronic neurodegenerative disorders, such as cerebral ischemia, Alzheimer's disease and Parkinson's disease.
Poisoning the Well: Neurotoxic Metals, Water Treatment, and Human Behavior http://www.alkalizeforhealth.net/Lpoison.htm
Summary: Heavy metals compromise normal brain development and neurotransmitter function, leading to long-term deficits in learning and social behavior.
Vaccinated Children Two And A Half Times More Likely To Have Neurological Disorders
http://www.medicalnewstoday.com/articles/75333.php
From Article:
For older vaccinated boys in the 11-17 age bracket, the results were even more pronounced. Vaccinated boys were 158% more likely to have a neurological disorder, 317% more likely to have ADHD, and 112% more likely to have autism. Complete survey results are available at
http://www.GenerationRescue.org.
Autism: a Novel Form of Mercury Poisoning
http://www.autism.com/triggers/vaccine/mercury.htm
From Article:
Autism is a neurodevelopmental disorder which has been characterized as "a disorder of neuronal organization, that is, the development of the dentritic tree, synaptogenesis, and the development of the complex connectivity within and between brain regions" . Depressed expression of neural cell adhesion molecules (NCAMs), which are critical during brain development for proper synaptic structuring, has been found in one study of autism. Organic mercury, which readily crosses the blood-brain barrier, preferentially targets nerve cells and nerve fibers; primates accumulate the highest Hg-levels in the brain relative to other organs. Furthermore, although most cells respond to mercurial injury by modulating levels of glutathione (GSH), metallothionein, hemoxygenase, and other stress proteins, neurons tend to be “markedly deficient in these responses” and thus are less able to remove Hg and more prone to Hg-induced injury. In the developing brain, mercury interferes with neuronal migration, depresses cell division, disrupts microtubule function, and reduces NCAMs.
