Rna Definition and 53 Threads

Hello , is minor bases and Nucleoside the same thing ?

It takes awhile though! ... Popular article: https://www.quantamagazine.org/in-test-tubes-rna-molecules-evolve-into-a-tiny-ecosystem-20220505/ Technical report: https://www.nature.com/articles/s41467-022-29113-x Looks like we are starting to understand 'Life' and 'Evolution'. Cheers, Tom

It is well known that RNA viruses mutate very quickly. Hence, it is said that it is very hard to develop an effective vaccine against it. With HIV and influenza RNA viruses the scientific world is still facing difficulty in developing effective long-term vaccines against them. Most influenza...

From the Oligonucleotide Therapeutics Society: "Can Oligonucleotides Target RNA Splicing to Treat Disease?" https://www.oligotherapeutics.org/can-oligonucleotides-target-rna-splicing-to-treat-disease/

https://www.technologyreview.com/2021/02/05/1017366/messenger-rna-vaccines-covid-hiv/ I would expect Katalin Karikó and Drew Weissman to be awarded the Noble Prize in Physiology or Medicine. The technology may be applied to other viruses.

Simplistic Example Given - DNA - RNA AATGTA codes for a protein. 1. Does the inverse ATGTAA usually/ever code for a protein? 2. Does the reciprocal RNA TTACAT usually/ever code for a protein?

How can A, B, and C choices do with the CTD?

Today (AUG 1) is RNA Day, an international celebration of one of the most versatile biomolecules in existence. This year, in particular, we are reminded of the importance of RNA biology as a pandemic caused by an RNA virus has disrupted life worldwide. What are some areas of RNA research that...

Published this week in the journal Science, researchers report that they have devised a eight letter alphabet for DNA and RNA: The work builds off of previous work, which had expanded the genetic alphabet to six letters. The researchers call their eight-lettered nucleic acids "hachimoji,"...

Today (AUG 1) is RNA Day, an international celebration of one of the most versatile biomolecules in existence. What are some areas of RNA research that excite you most? Some of the most intriguing areas of current research to me (with example links for further reading): The role of RNAs in...

Homework Statement I’m reading my way through the Brittanic.com article on abiogenesis and I have a question regards the following line taken from the article;[/B] “...a single RNA catalyst could have produced mulitiple living forms...” Q. Is this implying that RNA could have existed...

Homework Statement [/B] I am reviewing an example on the basics of the genetic code; this example is listed at the bottom of the following webpage: https://www.atdbio.com/content/14/Transcription-Translation-and-Replication.I have produced the example below and added Roman numbers to better...

https://www.quantamagazine.org/lifes-first-molecule-was-protein-not-rna-new-model-suggests-20171102/

Moderna Therapeutics has apparently been working on developing RNA for drug uses with a minimum of publicity, publishing mostly just patents and getting a lot of investment capital. Their goal is to make injectable RNAs that will be translated into specific proteins. This approach could be...

A Morpholino antisense drug has been approved by the US FDA. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm521263.htm This drug binds to complementary RNA to change biology, in this case altering the splicing of the protein that, when mutated, can cause Duchenne muscular...

I stumbled upon this publication (News at phys.org). As far as I understand, it is a big step towards replicating RNA systems. They found an RNA enzyme that can synthesize longer RNA molecules, and fully replicate shorter RNA molecules - completely without proteins. It cannot replicate itself...

How exactly does RNAi help in fighting against cancer gene ?

If RNA polymerase moves from the 3' to 5' end of the template strand to synthesize an mRNA strand from the 5' to 3' end (http://www.ncbi.nlm.nih.gov/books/NBK22085/), how come promoters are located on the 5' end (said in my Biology class)? It was also mentioned that while RNA polymerase moves...

I was wondering if anyone knew what happens to a protein that gets wrongly assembled due to a mutated RNA? Does it just do a slightly different or very destructive action in the organism, or does the organism catch it and kick it out? Also an extra side question: Speaking of mutations of RNA...

Homework Statement UV Rays is said to induce point mutations which get incorporated during the DNA replication process. These mutations are corrected by the excision repair mechanism of the DNA polymerase but sometimes they might be left out. In one of such cases, point insertions were...

Homework Statement Val-tRNA val is the tRNA that carries valine to the ribosome during translation. Which of the following sequences gives an appropriate anticodon for this tRNA? A. CAU B. AUC C. UAC D. GUG Homework Equations There are four different codons for Valine: GUU, GUC, GUA, and...

Hey, I'm looking for any books that contain anything on RNA and Graph Theory, was hoping if anyone has any recommendations or can at least point me in the right direction. I've already read through the section on this topic in Goodaire and Parmenter's 'Discrete Mathematics with Graph Theory'...

Hi, I have a simple semantics question. I have been reading some literature that seems to consider RNA Primers as part of Okazaki fragments, but this should not be so because Okazaki Fragments by definition are just the DNA portions synthesized on the lagging strand. Any...

1. The problem in attachments Homework Equations 3. RNA destroyed means no proteins (enzymes) formed, however if some areas showed no color, does that mean other areas did? I'm pretty sure the answer is D but making sure

Hi, The question is the same as the title : Are ribosomes complexes of protein and RNA? I read that in a book and though I have no idea what ribosomes are made of I thought it did'nt make sense that they are complexes of protein and DNA. Help?

Hello! I'm looking for information, articles and theories about which could have been the original molecule of life: DNA, RNA or protein. Most of what I've found is based on the RNA world theory (which I think is pretty well explained and sounds plausible), but I haven't found out any...

Slow Pace of RNA RESEARCH WHY? I was talking to a grad student in my lab the other day and we couldn't agree on why it take so long to discover gene regulation by RNA processing? I mean we knew about DNA and RNA decades ago why did it take so long to figure out that they can be regulated...

Hello! I'm guessing nanotechnology poses many difficulties, especially when using synthetic materials to manufacture complicated machines on such a small scale. I was thinking, therefore, that, if the mechanisms of protein folding are figured out, then mRNA sequences can be designed to...

Hi all, I have been reading some papers where they talk about RNA transcription rates in operons namely lac and unc. Can anyone tell me how does one go about in calculation of these rates? Thanks, Nancy

Homework Statement An enzyme called "RNA polymerase" catalyzes the formation of messenger RNAs. Therefore, we know that each RNA polymerase molecule: Homework Equations a.could be classified as a nucleic acid. b.can participate in mRNA formation multiple times. c.is found only in...

How does rna polymerase "read" dna ?? How does RNA polymerase "read" DNA? What i mean is ,after all,the polymerase is just a molecular complex,not an intelligent organism?how does it "know" that it has to combine 'A' to 'U' and 'G' to'C'. What is the exact mechanism involved??

I asked this question in some other place but they had simply said that .. the DNA polymerase don't have the ability to start DNA polymerization but I already know that and it doesn't answer my question. RNA is not much different from DNA (virtually same as far as polymerization reaction is...

Homework Statement Consider the genome of an RNA phage where only one strand of RNA is packaged into the phage. How can this phage produce many offspring that all have the same strand of RNA? Homework Equations The Attempt at a Solution mitosis?

Homework Statement Dear All, I have a question regarding RNA translation. Firstly, my book states that Amino-Acids are binded to tRNA through AA-Activation which is possible through ATP->AMP. The AA will then bind to the acceptor stem near 3' end. My question is: a) Each strand of...

hi, DNA and RNA seem to be very peculiar molecular structures that are able to replicate themselves, and they are unique regarding this point, right?. But which chemical "magical" phenomena is responsible for this ability to reproduce?

Homework Statement After isolating the same mRNA transcripts of the same gene, why are some transcripts bigger than others? Homework Equations The Attempt at a Solution

I had a question about how the RNA processing occurs. I know that the RNA is transcribed off the DNA, and then the introns are removed(sometimes in different orders), and then the capping occurs. My question is whether or not different segments of RNA can fuse together before during the...

which DNA and RNA bases contain a carbonyl group? Which DNA and RNA bases are primary amines? Thanks for any help

DNA strand (template strand) it is transcribing? Why couldn't it move toward the 3' end? Please explain with as much clarification as possible. I understand the 5' end is the phosphate group end of a nucleotide, and 3' end is the hydroxyl (-OH) end. I also know that nucleotides are only added...

How does RNA "know" which DNA strand is the template strand?

I've been purifying RNA for RT-PCR cloning. I have been using the same type of kit (Promega Total RNA Kit). My 260/280 ratio has been between 1.9-2.1, which is good. However I just ran a new set of samples and the ratio is down to 1.7 which isn't so great. This might mean I have a lot of DNA...

Can RNA interference be used to stop the expression of SIR2 and SCH9 genes? Is it unknown whether or not it can? never mind about the 3rd question found out the only difference was whether or not the change is inherited

The article Danish researchers solve virus puzzle here describes how physicists and biologists work together to examine how viruses are produced by a cell. As far as I understand, every human cell has RNA which contains the 'recipe' on how to build proteins. The human cell also contains...

Since nucleotides are molecules, how does quantum mechanics pertain to DNA and RNA? I have heard there is the study of stability of the DNA and RNA molecules, for instance. What does DNA and RNA actually look like -- as opposed to textbook drawings which illustrate spherical balls attached to a...

Does the single-handedness of DNA and RNA indicate that life originated few times, if more than once? What might the sameness between early sequences (in bacteria, say) indicate in this regard?

Why there is uracil in RNA instead of thymine and why not in DNA? Thanks.

Do you have any good protocols for measuring the concentration of RNA? The ones i have they seem to be very confused. Thanks.

Are the whole processes of DNA, RNA, ribosomes, amino acids and proteins all just "chemical reactions" or is there something more to it? I know the way it works from DNA to protein but why? I understand this question might have a very complex anwser but a brief explanation would be...

T7 RNA polymerase for SP6 promoter? hi guys! i don't know how many molecular biologists are here, but i try my luck anyway :rolleyes: my question is, is that possible using T7 RNA polymerase for transcribing genes under the control of SP6 promoter? hopes for replies! thanks alot!

RNA Splicing Software ? What is the Softwares used to predict RNA splicing sites ?