What's the Difference Between Enhancer Fusion and Promoter Fusion?

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The discussion centers on the concept of fusion in genetics, specifically differentiating between enhancer fusions and promoter fusions. Fusion refers to the creation of a single DNA sequence by joining two or more sequences. An enhancer fusion occurs when one of the sequences is an enhancer, while a promoter fusion involves a promoter sequence. The conversation highlights that promoter-enhancer fusions can also exist, exemplified by the use of constructs in transgenic flies. Additionally, it notes that there is no strict distinction between promoters and enhancers, indicating a degree of overlap in their functions and roles in gene expression.
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Also how is it different (if at all) from promoter fusion?
 
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Fusion just means you make a single DNA sequence by joining 2 or more other sequences. If one of the sequences is an enhancer, then the resulting joined sequence is an enhancer fusion. If one of the sequences is a promoter, then the resulting joined sequence is a promoter-fusion. You can, of course, get promoter-enhancer fusions, eg. "The process was analysed in transgenic flies carrying beta 1 enhancer-hsp70 promoter-lacZ fusion constructs."

There isn't a strict distinction between promoters and enhancers.
http://www.ncbi.nlm.nih.gov/books/NBK21745/#A2566
 
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Thanks a bunch.
 
Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom

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