To calculate the resistance of a hollow sphere with internal radius R1 and outer radius R2, the relevant formula is R = ρ * l / A, where ρ is resistivity, l is the thickness (R2 - R1), and A is the cross-sectional area. The resistance is determined by considering the area of the inner and outer surfaces and treating the hollow sphere as a series of thin shells. The approach involves integrating the resistance contributions from each shell to find the total resistance from the inner to the outer surface. This method simplifies the problem by using the properties of a trapezoid for the cross-sectional areas. Understanding these concepts is essential for solving the problem effectively.