To calculate the torque required to rotate a 10 cm diameter axle with a 100 cm diameter wheel hanging a 10 kg weight, the formula T = Fr applies, where F is the force due to the weight and r is the radius of the axle. The minimum torque needed to prevent the weight from falling is calculated as 981 Nm for 10 kg and increases to 1079 Nm for an 11 kg weight. Additional torque is necessary to account for the desired acceleration and the moment of inertia of the system. The mass of the axle and wheel must be sufficient to withstand the forces applied without breaking. Understanding the system's acceleration and friction is crucial for accurate calculations.