Chiral Center Priority: Determining R and S Configurations Using CIP Rules

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The discussion revolves around determining the R and S configurations of a chiral center carbon attached to H, CH3, OH, and CH2CH2OH. The main confusion arises from prioritizing the OH and CH2CH2OH groups, both containing hydroxyl groups. According to Cahn-Ingold-Prelog (CIP) rules, the OH group directly attached to the chiral center takes priority over CH2CH2OH due to its direct connection. The proposed priority order is H (4), CH3 (3), CH2CH2OH (2), and OH (1), leading to a clockwise arrangement, indicating an R configuration. The discussion emphasizes the importance of following CIP rules for accurate configuration determination.
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Homework Statement



Say you have a chiral center carbon, attached to it are a H, a CH3, an OH, and a CH2CH2OH. The H is pointing away from you, and in a clockwise direction it goes, CH3, OH, CH2CH2OH

My question is what is the priority of this? My main confusion is in the fact that since both the OH and CH2CH2OH have an OH in them, does the OH take priority since it is directly connected to the carbon? As in, do you just stop right there, and you know it has more priority?

The Attempt at a Solution



This is what I THINK it should be...

Priorities:
H: (4)
CH3: (3)
OH: (1)
CH2CH2OH: (2)

Therefore, it goes from OH, to CH2CH2OH, to CH3, which is a clockwise direction, therefore it is R ?
 
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RyanTAsher said:
R and S.
Then, one uses "C-I-P" detailed in the link.
 
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