Electrophysiology Quick Homework Problems

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Discussion Overview

The discussion revolves around solving homework problems related to electrophysiology, specifically focusing on an RC circuit and the properties of neuronal membranes. Participants seek assistance with the equations and calculations involved in these problems.

Discussion Character

  • Homework-related
  • Mathematical reasoning

Main Points Raised

  • Participants present two questions regarding an RC circuit and neuronal membrane properties, seeking help with solutions.
  • One participant attempts to calculate the resistance per cm2 of a neuronal membrane using the time constant and capacitance, arriving at a value of 1000 Ω per cm2.
  • There is uncertainty regarding how to determine the total current needed for calculating the number of ion channels per µm2 of neuronal membranes.
  • Another participant suggests using the equation V(t) = V(1-e-t/RC) for the voltage across the capacitor in the RC circuit.
  • There is a follow-up question about substituting t=2RC into the voltage equation to find the voltage at that time.

Areas of Agreement / Disagreement

Participants are generally engaged in exploring the problems, but there is no consensus on the solutions or methods to approach the calculations. Uncertainty remains regarding the total current and its role in the second part of the homework.

Contextual Notes

Limitations include potential missing assumptions in the calculations and the need for clarification on the total current for the ion channel question.

wubwubs
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Homework Statement


Hi guys,
I've been trying to solve these two questions for the last hour and can't seem to find the solution, any help would be very much appreciated. :smile:

1. An RC circuit is given a step voltage (charging) of V at t = 0 seconds. What is the value of voltage at t = 2RC?

2. If the conductance of a single ion channel is 1pS and its capacitance per cm2 is 1mF and the time constant for a human neuron is 1ms:
(a) What is the resistance per cm2 of a neuronal membrane?

(b) How many ion channels on average must there be in one µm2 of neuronal membranes?

Homework Equations


T = RC
Tau = Resistor x Capacitor

The Attempt at a Solution


1. Tried attempting this question for a solid hour and not sure where to begin.
2.
(a) 1 x 10^-3ms = R x (1 x 10^-6F)
R = 1000W per cm2
(b) I know to divide the total current by the single current but I can't seem to find the solution to identify the total current.
 
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wubwubs said:

Homework Statement


Hi guys,
I've been trying to solve these two questions for the last hour and can't seem to find the solution, any help would be very much appreciated. :smile:

1. An RC circuit is given a step voltage (charging) of V at t = 0 seconds. What is the value of voltage at t = 2RC?

2. If the conductance of a single ion channel is 1pS and its capacitance per cm2 is 1mF and the time constant for a human neuron is 1ms:
(a) What is the resistance per cm2 of a neuronal membrane?

(b) How many ion channels on average must there be in one µm2 of neuronal membranes?

Homework Equations


T = RC
Tau = Resistor x Capacitor

The Attempt at a Solution


1. Tried attempting this question for a solid hour and not sure where to begin.
2.
(a) 1 x 10^-3ms = R x (1 x 10^-6F)
R = 1000W per cm2
(b) I know to divide the total current by the single current but I can't seem to find the solution to identify the total current.
Welcome to the PF.

On question -1-, what is the equation for v(t) for an RC circuit that starts charging at t=0? You are correct that the time constant is RC, but how is that used in the actual equation?
 
berkeman said:
Welcome to the PF.

On question -1-, what is the equation for v(t) for an RC circuit that starts charging at t=0? You are correct that the time constant is RC, but how is that used in the actual equation?

Hi and thank you for the reply,
I believe the equation is V(t) = V(1-e^-t/RC). If you require additional information please ask, and thank you for the help.
 
Assuming the equation is correct, any particular reason to not just plug t=2RC into?
 

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