Albert Hoffman, the inventor of LSD, passed away at the age of 102, prompting discussions about the effects of hallucinogens on mental health and longevity. While some argue that LSD can lead to severe psychiatric issues, others highlight that many users experience no negative effects. The conversation also touches on Hoffman's legacy and the historical context of LSD's acceptance in scientific circles, with references to Kary Mullis's controversial paper published while under the influence. Concerns about the potential for mental health crises following LSD use are noted, yet the debate continues about the drug's overall impact and the need for further research. Ultimately, the discussion reflects a complex view of LSD, balancing its risks and potential benefits.