A user is seeking to boost the output voltage from a Peltier cooler, currently generating around 55mV, to approximately 3V without altering the temperature conditions. Suggestions include using step-up converters, with specific references to devices like the LTC3108, which operates from inputs as low as 20mV. There is a discussion on the limitations of voltage multipliers and the challenges of using multiple Peltiers in series due to size constraints. The importance of maintaining total power during conversion is emphasized, along with the potential for energy harvesting solutions. Overall, the conversation focuses on finding effective methods to achieve the desired voltage increase from low input levels.