Once you've labeled a current though a component, that's the current that is associated with it. It doesn't change if you apply KVL to different loops that happen to share that component. So ##I_3## flows through the 10 Ω resistor, in the same direction as you chose it, for each KVL equation that contains that resistor. So just be careful of the signs of the terms: if you "KVL walk" over a resistor against the flow of the current, then you will "see" a potential rise instead of a drop.
In your second equation above, you are "walking" clockwise around the loop, so when you traverse the 10 Ω resistor you are proceeding upwards, against the flow of ##I_3##. Will you see a potential drop or a potential rise as a result?