How Do You Calculate the Relative Growth Rate of E. coli in a Nutrient Broth?

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Homework Help Overview

The problem involves calculating the relative growth rate of Escherichia coli in a nutrient broth, given its doubling time and initial population. The context is rooted in exponential growth models.

Discussion Character

  • Exploratory, Mathematical reasoning, Problem interpretation

Approaches and Questions Raised

  • Participants discuss the application of exponential growth equations and the relationship between population size and growth rate. There are attempts to derive the growth rate using provided equations and initial conditions.

Discussion Status

Some participants have provided guidance on how to set up the equations to find the growth rate, while others have shared their attempts and expressed uncertainty about their calculations. The discussion reflects a collaborative effort to clarify the problem and explore different approaches.

Contextual Notes

Participants are working under the constraints of a homework assignment, which may limit the information they can use or the methods they can apply. There is an emphasis on understanding the relationship between the growth rate and the doubling time of the bacteria.

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Homework Statement


-
A common inhabitant of human intestines is the bacterium Escherichia coli. A cell of this bacterium in a nutrient-broth medium divides into two cells every 20 minutes. The initial population of a culture is 63 cells.
-
(a) Find the relative growth rate.

Homework Equations


Well this has to do with exponential growth and decay. So equations that could apply are

\frac{dy}{dt}=ky
where y is some function, k is a constant and dy/dt is a change in that function

y(t)=y_0e^k^t

where y of t is a function, y of 0 is an initial value, k is a constant and t is time

y^-^1* \frac{dy}{dt}=k

The Attempt at a Solution



(a) Find the relative growth rate in cells per hour.

well I thought since I know the change in the change of the number of bacteria per minute and the starting number of bacteria, I thought i could do this-

\frac{1}{63}*\frac{2}{20}

\frac{1}{63}*\frac{1}{10}

\frac{1}{630} cells per minute

\frac{60}{630}cells per hour

.095cells per hour

that answer is wrong. I don't know how to go about this as you can clearly tell. can someone give me a kick start?

thanks :)
 
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Plug in the values to:

y(t) = y_0e^{kt}

After 20 min you have twice as many...

126 = 63 e^{k(20)}

Now solve for k. Then you will have the equation for how many there are after t min.
 
Start with:
y(t)=y_{0}e^{kt}
Since we have:
63=y(0)=y_{0}, we ave determined ONE of the two constants, y_0.

The relative growt rate is, indeed, k.
We know that after t=20 minutes, the population has doubled.
Thus, we have:
2y_{0}=y(20)=y_{0}e^{20k},
which means:
e^{20k}=2\to{k}=\frac{\ln(2)}{20}
Thus, we get:
y(t)=63e^{\frac{t\ln(2)}{20}}=63*2^{\frac{t}{20}}
if you want to make the doubling time explicit, t being understood to be measured in minutes.
 
Thanks guys :). I knew I kind of overlooked this question. I should have known better. k=2.07 cells per hour. I got part a right and once I got that, all the other parts of the question (a-e) fell right out. I thank all of you.

-Hover
 

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