Measuring the direction of subpicoamp currents is feasible, particularly in the femtoampere range, using specialized commercial instruments that can detect currents below a picoampere. The measurement method often involves translating current into voltage through a high impedance, though this approach has limitations due to factors like Johnson noise. Instruments such as those from Keithley provide practical solutions for these measurements. Additionally, resources from Analog Devices and Texas Instruments offer further insights into best practices and device specifications. Accurate measurement depends on the impedance used and the specific conditions of the setup.