Negative acceleration can indicate either a change in direction or deceleration, depending on the context of the initial and final velocities. To determine the nature of the acceleration, both initial and final velocities must be analyzed alongside the acceleration value. A negative acceleration implies that the acceleration is acting in the direction opposite to the velocity, but this does not clarify whether the object is slowing down or changing direction. If the velocity is negative, negative acceleration could actually mean the object is speeding up in the reverse direction. Understanding the relationship between acceleration and velocity is crucial for accurate interpretation.