lets try it. {1} does not seem to work. {1,2} ok
{1,2,3,4} ok,
it looks likely from now on, but why don't we use the theorem behind "mills constant"? (I just heard of this today, on this site.)
i.e. there is a constant K such that for any prime p, the next prime is closer than K p^(5/8), in particular it is closer than Kp.
so once p gets larger than K, we have that the next prime is closer than p^2.
hence the next prime is smaller than p+p^2 = p(1+p), which is a lot smaller than 2^p. so this says that in any sequence of integers, {1,2,...,p,...,n} where p is the alrgest prime, then n is smaller than the next larger prime hence n is smaller than 2^p. so this is certainly true eventually, i.e. for large n.
but it is probably easy to prove it is always true. i just do not see it right now.