The discussion centers on the existence of electrons, emphasizing that while no physicist has directly observed an electron, substantial experimental evidence supports their existence, unlike ghosts. It highlights that evidence for electrons includes repeatable experiments and phenomena like shot noise in audio amplifiers, which correlates with the quantized nature of electric charge. The argument against the analogy of ghosts is strengthened by the lack of empirical evidence for their existence. The conversation also touches on the limitations of human senses in detecting phenomena, underscoring that seeing is not the only valid form of evidence in physics. Overall, the existence of electrons is well-supported by scientific data, contrasting sharply with the unfounded belief in ghosts.