In a see-saw scenario with a 100 lbs person and a 50 lbs person, the heavier individual must sit closer to the fulcrum for balance. This is due to the principle of torque, where the weight and distance from the fulcrum must equate for equilibrium. If the heavier person weighs twice as much, they need to sit half as far from the fulcrum compared to the lighter person. The discussion emphasizes that there are no stupid questions, and understanding these physics principles is important regardless of personal challenges. Balancing weights on a see-saw relies on the relationship between weight and distance from the fulcrum.