The user is experiencing issues with two CD drives, D: and E:. The D: drive is unresponsive and won't open, while the E: drive is not recognized by the computer despite opening normally. The user recently reformatted the hard drive and successfully used the E: drive to install software after the reformat. The D: drive appears in the Device Manager as functioning, but the E: drive does not show up at all. Both drives are listed during the initial boot sequence. Troubleshooting suggestions include checking the BIOS for drive recognition, ensuring proper connections, and verifying if any recent software installations might have caused conflicts. The user is currently trying to install new webcam software, which is hindered by the drive issues.