Why optically active molecules rotate light?

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SUMMARY

The discussion centers on the optical activity of chiral molecules, specifically R-alanine, which rotates z-polarized light clockwise when its COOH group is oriented along the positive y-axis. The inquiry explores why reversing the orientation of the COOH group does not result in an opposite rotation. The conversation references helicenes as examples of chiral molecules with helical structures, illustrating the principles of optical activity and molecular symmetry.

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  • Understanding of chiral molecules and optical activity
  • Familiarity with molecular geometry and symmetry
  • Basic knowledge of polarized light and its interaction with matter
  • Concept of helices in three-dimensional space
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  • Research the principles of optical isomerism in organic chemistry
  • Study the molecular structure and properties of helicenes
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Say, we have a solution of pure form of R-alanine. Say, the molecule has it's COOH group directed along positive y-axis and rotates the z-polarized light clockwise - the question is why the same molecule with it's COOH group in negative y direction won't do the opposite.
 
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Consider a simpler example, a helix. How does a helix look like when you rotate it by 180 deg?
An example of a chiral molecule with a helical structure are the helicenes:
http://en.wikipedia.org/wiki/Helicene
 
Fascinating :). Thank you for the reply, DrDu.
 

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