Cell membrane lipid peroxidaton

  • Thread starter Thread starter fxue
  • Start date Start date
  • Tags Tags
    Cell Membrane
AI Thread Summary
The discussion centers on the impact of lipid peroxidation on the stiffness of cell membranes. A participant shares a paper that explores oxidative stiffening of erythrocyte membranes, particularly in sickle cell disease, suggesting that membrane protein oxidation contributes to stiffness. However, it is noted that while lipid peroxidation is destructive, it may not directly cause increased stiffness in lipid components. The inquiry emphasizes the need for further insights or literature on the relationship between lipid peroxidation and membrane stiffness.
fxue
Messages
1
Reaction score
0
Hi Guys,

I am new to this forum and would like to take this chance to say hello to everyone here.

Basically, my question is about the mechanical translation of cell membrane lipid peroxidation. I am wondering if lipid peroxidation has any impact on the stiffness of cell membrane. If so, is there any guideline or judgement of it?

If anybody has read about anything related, please let me know or send me the paper or book.

Thanks in advance,
Feng
 
Biology news on Phys.org
Here's a paper re oxidative stiffening of erythrocyte membranes. The authors believe that the stiffening is related to the oxidation of membrane proteins in patients with sickle cell disease. While oxidation of the lipid structure of cell membranes by free radicals is progressive and destructive, I'm not aware that it involves stiffening due to oxidation of lipid components.

http://bloodjournal.hematologylibrary.org/cgi/content/short/76/5/1015
 
Last edited by a moderator:

Thread 'Body dysmorphic disorder (BDD)'

https://www.nhs.uk/mental-health/conditions/body-dysmorphia/ Most people have some mild apprehension about their body, such as one thinks their nose is too big, hair too straight or curvy. At the extreme, cases such as this, are difficult to completely understand. https://www.msn.com/en-ca/health/other/why-would-someone-want-to-amputate-healthy-limbs/ar-AA1MrQK7?ocid=msedgntp&cvid=68ce4014b1fe4953b0b4bd22ef471ab9&ei=78 they feel like they're an amputee in the body of a regular person "For...
View full post »
Thread 'Did they discover another descendant of homo erectus?'

Thread 'Did they discover another descendant of homo erectus?'

The study provides critical new insights into the African Humid Period, a time between 14,500 and 5,000 years ago when the Sahara desert was a green savanna, rich in water bodies that facilitated human habitation and the spread of pastoralism. Later aridification turned this region into the world's largest desert. Due to the extreme aridity of the region today, DNA preservation is poor, making this pioneering ancient DNA study all the more significant. Genomic analyses reveal that the...
View full post »

Thread 'Here comes COVID-19 version BA.2, BA.4, BA.5,...'

Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom
View full post »

Similar threads

What are the lipids on the double membrane of a eukaryote cell's nucleus?
Replies
4
Views
2K
Medical Tensile strength of cell membranes
Replies
11
Views
2K
Can a biomolecule from one cell's cellular component migrate
Replies
4
Views
1K
What might cell membranes look like on Titan?
Replies
39
Views
9K
Magnetic torque on cell membrane by MNPs
Replies
3
Views
2K
Question about plasma membranes
Replies
3
Views
4K
COVID Precisely how does Pfizer's Covid-19 mRNA vaccine work?
Replies
31
Views
6K
Can we calculate the exact number of receptors on E.Coli membrane?
Replies
5
Views
4K
Medical Why Should We Worry About Necrosis Despite Cell Regeneration?
Replies
2
Views
1K
Diffusion across a cell membrane?
Replies
1
Views
4K

Hot Threads

Recent Insights

Back
Top