1. The problem statement, all variables and given/known data What would happen to the level of ATP synthesis in the respiratory chain if you make the intermembranal space more acidic more acidic? What if it were made more basic? 2. Relevant equations 3. The attempt at a solution ATP synthesis is triggered by chemiosmosis - the flow of H+ protons down their concentration gradient, through ATPase. ATPase uses this motion to synthesise ATP. Adding acid means adding more protons. Does this mean that ATP production will increase? Could acidic conditions damage the chain?