E1 reaction on levosalbutamol

  • Chemistry
  • Thread starter duchuy
  • Start date
  • #1
79
3
Homework Statement:
Where will the E1 reaction occur
Relevant Equations:
x
1618497592282.png

Hi,
I have to determine the reaction mechanism of this molecule.
Can someone please explain to me why the reaction would occur on OH (A)?
Is it bc you can't have 2 pi bonds next to each other and OH(A) is the only polarised bond in the molecule where it would easily break off and form a double bond?
Thank you!
 

Answers and Replies

  • #2
TeethWhitener
Science Advisor
Gold Member
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Try drawing the reaction mechanism for each case and see if you can get any further. Unfortunately there’s no great way to do chemical structure drawings in the forum, but feel free to post pictures of your work and I’ll take a look.
 
  • #3
206
106
Hint: The stability of the carbocation intermediate plays a role.
 
  • #4
chemisttree
Science Advisor
Homework Helper
Gold Member
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A good rule of thumb is to use the catalyst in the first step. Doesn’t always work but it usually does.
 

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