To calculate the voltage across each resistor in a mixed circuit, first identify whether the resistors are in series or parallel. For series resistors, add their resistances to find the total resistance and use Ohm's Law (V = I * R) to determine the current. The voltage drop across each resistor can then be calculated using the formula V = I * R for each individual resistor. If resistors are in parallel, use the formula 1/R_total = 1/R1 + 1/R2 to find the equivalent resistance. Accurate calculations require converting units correctly, such as converting milliamps to amps when applying Ohm's Law.